Neuroprotective Role of Chrysin Against Bupivacaine Induced Apoptosis and Oxidative Stress in SH-SY5Y Cell Line
نویسندگان
چکیده
Chrysin, a natural flavonoid, has strong neuroprotective effect in many neurodegenerative diseases. Therefore, we aimed to investigate the of chrysin against bupivacaine-induced neurotoxicity SH-SY5Y cells. According results XTT analysis, non-toxic concentration was determined and cells were treated with bupivacaine alone together this dose. RT-qPCR level caspases increased group only compared control group, while expression antioxidant enzymes decreased. When alone, it that decreased which together, increased. ELISA results, SOD CAT activities group. presence alone. The obtained data showed may play role by inducing inhibiting apoptosis
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ژورنال
عنوان ژورنال: Biotech studies
سال: 2023
ISSN: ['2687-3761']
DOI: https://doi.org/10.38042/biotechstudies.1273778